The role of repeated aspirations in the treatment of tubercular cervical lymphadenitis

  • Dr. Reema Goswami Associate Professor, Department of ENT, Bundelkhand Medical College, Sagar, M.P. India
  • Dr. Amar Gangwani Associate Professor, Department of Pathology, Bundelkhand Medical College, Sagar, M.P. India
  • Dr. Devendra Goswami TB Chest Specialist, District Hospital, Sagar, M.P., India
  • Dr. Pranjal Shrivastav Assistant Professor, Department of Community Medicine; Bundelkhand Medical College, Sagar, M.P. India
Keywords: Tubercular Lymphadenitis, Abscess, Fistula, Aspiration

Abstract

Introduction: Tubercular lymphadenitis is the most common form of extrapulmonary tuberculosis. Tubercular lymphadenopathy can progress to abscess and fistula formation. Further during the course of treatment paradoxical upgrading reaction of lymphnodes like appearance of new lymphnodes and sinus formation can occur.

Objective: The aim of the study was to evaluate the role of repeated aspirations as an adjunct to ATT in the treatment of tubercular lymphadenitis presenting with abscess.

Material and Methods: The study involved 180 cases of cervical lymphadenopathy who presented in the ENToutpatient Department of Bundelkhand Medical College Sagar between Jan 2016 to Sep 2017. 102 cases were diagnosed by FNAC and 3 cases were diagnosed by excision biopsy as tubercular lymphadenitis. Only new cases of were included Out of the 105 cases of diagnosed with tubercular lymphadenitis 15 cases presented with cold abscess initially. All thepatients were started onanti-tubercular treatment. 10 cases developed abscess during the course of treatment. All cases presenting with abscess were subjected to repeated aspiration biweekly.

Results: All cases of tubercular lymphadenitis and abscess showed complete recovery with 6 months of treatment.

Conclusion:Repeated aspirations in cold abscess as an adjuvant to ATT is a less invasive procedure than surgical excision and reduces the complications like sinus formation. Close supervision by the ENT specialist is mandatory during the course of medical treatment to combat paradoxical upgrading reactions especially abscess formation.

Downloads

Download data is not yet available.

References

1. Manjareeka M, Nanda S. Prevalence of HIV infection among tuberculosis patients in Eastern India. J Infect Public Health. 2013 Oct;6(5):358-62. doi: 10.1016/j.jiph.2013.04.004. Epub 2013 Jun 6.[pubmed]

2. Appling, D. And Miller, R. Mycobacterial Cervical Lymphadenopathy. The Laryngoscope, 1981;91(8):1259-1266.[pubmed]

3. Kent DC. Tuberculous lymphadenitis: not a localized disease process. Am J Med Sci. 1967 Dec;254(6):866-74.[pubmed]

4. Gupta P. Difficulties in managing lymph node tuberculosis [Internet]. Lungindia.com. 2019 [cited 24 January 2019]. Available from: http://www.lungindia.com/text.asp?2004/21/4/50/

5. Hawkey CR, Yap T, Pereira J, et al. Characterization and management of paradoxical upgrading reactions in HIV-uninfected patients with lymph node tuberculosis. Clin Infect Dis. 2005 May 1;40(9):1368-71. Epub 2005 Mar 23.[pubmed]

6. Cheung WL, Siu KF, Ng A. Tuberculous cervical abscess: comparing the results of total excision against simple incision and drainage. Br J Surg. 1988 Jun;75(6):563-4.[pubmed]

7. Baskota DK, Prasad R, Kumar Sinha B, et al. Distribution of lymph nodes in the neck in cases of tuberculous cervical lymphadenitis. Acta Otolaryngol. 2004 Nov;124(9):1095-8.[pubmed]

8. Mittal P, Handa U, Mohan H, et al. Comparative evaluation of fine needle aspiration cytology, culture, and PCR in diagnosis of tuberculous lymphadenitis. Diagn Cytopathol. 2011 Nov;39(11):822-6. doi: 10.1002/dc.21472. Epub 2010 Nov 2.[pubmed]

9. Gupta SK, Chugh TD, Sheikh ZA, et al. Cytodiagnosis of tuberculous lymphadenitis. A correlative study with microbiologic examination. Acta Cytol. 1993 May-Jun;37(3):329-32.[pubmed]

10. Maharjan M, Hirachan S, Kafle PK, et al. Incidence of tuberculosis in enlarged neck nodes, our experience. Kathmandu Univ Med J (KUMJ). 2009 Jan- Mar;7(25):54-8.[pubmed]

11. Khajanchi M, Bambarkar S, Gadgil A, et al. Cervical Node Tuberculosis in Adults of an Urban Middle Class Community: Incidence and Management. Indian J Otolaryngol Head Neck Surg. 2016 Sep;68(3):345-51. doi: 10.1007/s12070-015-0832-9. Epub 2015 Feb 4.

12. Jha B. Cervical tuberculous lymphadenopathy: changing clinical pattern and concepts in management. Postgraduate Medical Journal. 2001;77(905):185-187.

13. Treatment of tuberculosis [Internet]. Cdc.gov. 2019 [cited 24 January 2019]. Available from: https://www.cdc.gov/mmwr/PDF/rr/rr5211.pdf

14. Campbell IA, Ormerod LP, Friend JA, et al. Six months versus nine months chemotherapy for tuberculosis of lymph nodes: final results. Respir Med. 1993 Nov;87(8):621-3.[pubmed]

15. Yuen A, Wong S, Tam C, Chan S, Wei W, Lau S. Prospective randomized study of thrice weekly six-month and nine-month chemotherapy for cervical tuberculous lymphadenopathy. Otolaryngology Head and Neck Surgery. 1997;116(2):189-192.

16. Dowd C. The surgical treatment of tubercular cervical lymph-nodes a study of one hundred cases submitted to operation. Annals of Surgery. 1905;42(1):49-82.[pubmed]

17. Bryd R, Bopp K, Gracey D.The role of surgery in tuberculous lymphadenitis in adults [Internet]. Atsjournals.org. 2019 [cited 24 January 2019]. Available from: https://www.atsjournals

18. IndulkarP, AsthiA, AgarwalA, Indulkar M. Role of surgical intervention in treatment of tuberculous lymphadenitis in neck region. International Journal of Medical Science and Surgical Inventions 2017 4(5):2926-2928.

19. Kanjanopas K, Siripan N, Phoophitphong R. Tuberculous cervical lymphadenopathy and role of surgical treatment. South east Asian J Trop Med Public Health 2014 Nov, 45(6):1419-24.[pubmed]

20. Subrahmanyam M. Role of surgery and chemotherapy for peripheral lymph node tuberculosis. British Journal of Surgery. 1993;80(12):1547-1548..org/doi/abs/10.1164/arrd.1971.103.6.816

21. Koontz A. Tuberculous abscess successfully treated by aspiration and injection of streptomycin. Journal of the American Medical Association. 1949;141(7):459 –460. doi:10.1001/jama.1949.62910070002007a.

22. Lindeboom J, Kuijper E, Bruijnesteijn van Coppenraet E, Lindeboom R, Prins J. Surgical Excision versus Antibiotic Treatment for Nontuberculous Mycobacterial Cervicofacial Lymphadenitis in Children: A Multicenter, Randomized, Controlled Trial. Clinical Infectious Diseases. 2007;44(8):1057-1064.

23. Vidal C, Garau J. Systemic Steroid Treatment of Paradoxical Upgrading Reaction in Patients with Lymph Node Tuberculosis. Clinical Infectious Diseases. 2005;41(6):915-916.doi:10.1086/432807

24. Sharma SK, Mohan A. Tuberculosis. 1st ed. Noida: Jaypee Brothers Medical Publishers (P) Ltd; 2006:280-283
The role of repeated aspirations in the treatment of tubercular cervical lymphadenitis
CITATION
DOI: 10.17511/jooo.2019.i01.02
Published: 2019-03-31
How to Cite
Goswami, R., Gangwani, A., Goswami, D., & Shrivastav, P. (2019). The role of repeated aspirations in the treatment of tubercular cervical lymphadenitis. Tropical Journal of Ophthalmology and Otolaryngology, 4(1), 7-12. https://doi.org/10.17511/jooo.2019.i01.02
Section
Original Article