The Outcome Of Intratympanic Dexamethasone Treatment On Idiopathic Sudden Sensorineural Hearing Loss
Abstract
Introduction: Sudden sensorineural hearing loss is a frustrating symptom which when detected early can be treated with oral, intra venous or intra tympanic steroids.
Objective: To assess the effectiveness of intra tympanic steroid injection in idiopathic sensorineural hearing loss.
Method: A follow-up study done was among patients satisfying the case definition of idiopathic sudden sensorineural hearing loss. 35 Patients were evaluated by taking clinical history and performing complete physical examination. Pure tone audiogram was performed before and after intratympanic dexamethasone injection and recovery was analyzed.
Result: After statistical analysis overall outcome of the hearing was found better with intratympanic dexamethasone injection therapy.
Conclusion: Intratympanic dexamethasone therapy was useful in patients with idiopathic sudden sensorineural hearing loss.
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References
Hughes GB, Freedman MA, Haberkamp TJ, Guay ME. Sudden sensorineural hearing loss. Otolaryngol Clin North Am. 1996 Jun;29(3):393-405.
Mattox DE, Lyles CA. Idiopathic sudden sensorineural hearing loss. Am J Otol. 1989 May;10(3):242-7.
Ganesan P, Kothandaraman PP, Swapna S, Manchaiah V. A Retrospective Study of the Clinical Characteristics and Post-treatment Hearing Outcome in Idiopathic Sudden Sensorineural Hearing Loss. Audiol Res. 2017 Feb 15;7(1):168. doi: 10.4081/audiores.2017.168.
Itoh A, Sakata E. Treatment of vestibular disorders. Acta Otolaryngol Suppl. 1991;481:617-23. doi: 10.3109/00016489109131486.
Silverstein H, Choo D, Rosenberg SI, Kuhn J, Seidman M, Stein I. Intratympanic steroid treatment of inner ear disease and tinnitus (preliminary report). Ear Nose Throat J. 1996 Aug;75(8):468-71, 474, 476 passim.
Parnes LS, Sun AH, Freeman DJ. Corticosteroid pharmacokinetics in the inner ear fluids: an animal study followed by clinical application. Laryngoscope. 1999 Jul;109(7 Pt 2):1-17. doi: 10.1097/00005537-199907001-00001.
Fu Y, Zhao H, Zhang T, Chi F. Intratympanic dexamethasone as initial therapy for idiopathic sudden sensorineural hearing loss: Clinical evaluation and laboratory investigation. Auris Nasus Larynx. 2011 Apr;38(2):165-71. doi: 10.1016/j.anl.2010.07.008.
Whitaker S. Idiopathic sudden hearing loss. Am J Otol. 1980 Jan;1(3):180-3.
Chandrasekhar SS. Intratympanic dexamethasone for sudden sensorineural hearing loss: clinical and laboratory evaluation. Otol Neurotol. 2001 Jan;22(1):18-23. doi: 10.1097/00129492-200101000-00005.
Seggas I, Koltsidopoulos P, Bibas A, Tzonou A, Sismanis A. Intratympanic steroid therapy for sudden hearing loss: a review of the literature. Otol Neurotol. 2011 Jan;32(1):29-35. doi: 10.1097/mao.0b013e3181f7aba3.
Plaza G, Herráiz C. Intratympanic steroids for treatment of sudden hearing loss after failure of intravenous therapy. Otolaryngol Head Neck Surg. 2007 Jul;137(1):74-8. doi: 10.1016/j.otohns.2007.01.022.
Herr BD, Marzo SJ. Intratympanic steroid perfusion for refractory sudden sensorineural hearing loss. Otolaryngol Head Neck Surg. 2005 Apr;132(4):527-31. doi: 10.1016/j.otohns.2004.09.138.
Ahn JH, Han MW, Kim JH, Chung JW, Yoon TH. Therapeutic effectiveness over time of intratympanic dexamethasone as salvage treatment of sudden deafness. Acta Otolaryngol. 2008 Feb;128(2):128-31. doi: 10.1080/00016480701477602.
Copyright (c) 2022 Author (s). Published by Siddharth Health Research and Social Welfare Society
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