Fine needle aspiration cytology - a boon in the diagnosis of cutaneous metastasis

Sujata S. Giriyan; Rajesh H. Chandan; Kalyani G. Padgaonkar

doi:10.17511/jooo.2017.i02.03

Dr. Sujata S. Giriyan Professor and Head, Department of Pathology, Karnataka Institute of Medical Sciences, Hubli, Karnataka, India.
Dr. Rajesh H. Chandan Associate Professor, Department of Pathology, Karnataka Institute of Medical Sciences, Hubli, Karnataka, India.
Dr. Kalyani G. Padgaonkar Postgraduate, Department of Pathology, Karnataka Institute of Medical Sciences, Hubli, Karnataka, India.

DOI: https://doi.org/10.17511/jooo.2017.i02.03

Keywords: Cutaneous metastasis, Fine Needle Aspiration Cytology, osteosarcoma deposits

Abstract

Introduction: Cutaneous metastasis is an uncommon manifestation of visceral malignancy (0.8-5%) indicating a grave prognosis. Cutaneous metastasis manifests as nodules, ulceration, cellulitis or fibrotic processes. Lesions are solitary or multiple frequently found near the primary tumour. The most frequent organs presenting with cutaneous metastasis are breast, skin (melanoma), lung, colon, stomach, upper aerodigestive tract, kidney and the uterus. On histopathology, they can be classified as adenocarcinoma, squamous cell carcinoma, undifferentiated carcinoma and other miscellaneous types.

Case Reports:The present series involves 3 cases of cutaneous metastasis diagnosed on FNAC. First case of osteosarcoma presenting as swelling in femoral region, second case as swelling in cervical region from cancer oesophagus and third case presented with swelling over sternum from an unknown primary.

Conclusion:FNAC is the first line diagnostic procedure for diagnosis of cutaneous metastasis. It is inexpensive, simple and fast diagnostic tool confirming clinical diagnosis.

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References

1. Karki S, Pathak R, Manandhar U, Koirala S. Metastatic cutaneous and subcutaneous lesions: Analysis of cases diagnosed on fine needle aspiration cytology. Journal of Pathology of Nepal. 2011;1:37-40.

2. Bahadur AK, Ouseph MM, Rathi AK, Sharan GK, Sharma P, Shyama J et al. Osteosarcoma with cutaneous metastases. A case report. Acta cytol. 2007;1: 102-6.

3. Shaheen O, Ghibour A, Alsaid B. Esophageal Cancer Metastases to Unexpected Sites: A Systematic Review. Gastroenterology Research and Practice. 2017;2017: 1657310. doi:10.1155/2017/1657310.

4. Chauhan A, Sharma AK, Sunita BS. Cutaneous metastasis as primary presentation in unsuspected carcinoma esophagus: Report of two cases. J Can Res Ther. 2015;11:667

5. Mazumder G, Nath S. Role of fine needle aspiration cytology (FNAC) in the diagnosis of skin and subcutaneous lesions: a retrospective analysis. J Evolution Med Dent Sci 2016; 5(5): 292-295, DOI: 10. 14260/ jemds/2016/63

6. Mendonca B, Fernandes H, Rahim S, Ali S, Hegdekatte N. Cytology- a boon in the diagnosis of cutaneous and subcutaneous metastatic nodules. International Journal of Recent Trends in Science and Technology. 2015March; 14(2): 455-457.

7. Rosai and Ackermann surgical pathology, 10th edition, Volume 2.

8. Yasin SB, Bashir N, Khan SP. Evaluation of Metastatic Cutaneous Lesions on Fine Needle Aspiration Cytology: A Five Year Study. Annals of Applied Bio-Sciences. 2017 ; 4(1)

9. Erdemır AT, Atılganoglu U, Onsun N, Somay A. cutaneous metastases from gastric adenocarcinoma. indian journal of dermatology 2011;56(2):236-237.

10. Sharma S, Kotru M, Yadav A, Chugh M, Chawla A, Makhija M. Role of fine-needle aspiration cytology in evaluation of cutaneous metastases. Diagn Cytopathol. 2009 Dec; 37 (12): 876-80. doi: 10.1002/dc.21119.

11. Fyrmpas G, Barbetakis N, Efstathiou A, Konstantinidis I, Tsilikas C. Cutaneous metastasis to the face from colon adenocarcinoma. Case report. Int Semin Surg Oncol. 2006 Feb 2;3:2. doi: 10.1186/1477-7800-3-2.

12. Bansal R, Patel T, Sarin J, Parikh B, Ohri A, Trivedi P.Cutaneous and subcutaneous metastases from internal malignancies: an analysis of casesdiagnosed by fine needle aspiration. Diagn Cytopathol. 2011 Dec; 39 (12): 882-7. doi: 10.1002/dc.21485. Epub 2010 Nov 2.

13. Rolz-Cruz G, Kim CC. Tumor invasion of the skin. Dermatol Clin. 2008 Jan;26(1):89-102, viii.

14. Gattuso P, Castelli MJ, Reyes CV, Reddy V. Cutaneous and subcutaneousmasses of the chest wall: a fine-needle aspirationstudy.Diagn Cytopathol.1996 Dec; 15(5):374-6.

15. Brownstein MH, Helwig EB.Patterns of cutaneousmetastasis. Arch Dermatol. 1972 Jun;105(6):862-8.

16. Schwartz RA. Cutaneous metastatic disease. J Am Acad Dermatol.1995 Aug;33(2Pt1):161-82;quiz 183-6.

17. Didolkar MS, Fanous N, Elias EG, Moore RH. Metastaticcarcinomas from occultprimary tumors. A study of 254 patients. Ann Surg. 1977 Nov;186(5):625-30.

18. Osteen RT, Kopf G, Wilson RE. In pursuit of the unknown primary. Am J Surg. 1978 Apr;135(4):494-7.

19. Geramizadeh B, Marzban S, Karamifar N, Omidifar N, Shokripour M, et al. Diagnosis of Subcutaneous Metastatic Deposits by Fine Needle Aspiration. J Cytol Histol. 2012; 3:151

20. David O, Kluskens L, Reddy V, Gattuso P. Malignantcutaneous and subcutaneous abdominal walllesions: a fine-needle aspirationstudy. Diagn Cytopathol. 1998 Oct;19(4):267-9.

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